Q1What is Yunzhi,Polysaccharide Peptide（PSP）？

    Yunzhi is a form of polypore mushroom used in Asian cultures to treat serious illness. The name Yunzhi is commonly used in Traditional Chinese Herbal Supplement (TCHS). PSP stands for Polysaccharide Peptide, a protein-bound polysaccharide extracted from deep-layer-cultivated mycelia of the COV-1 strain of Yunzhi, also commonly known as Coriolus Versicolor or Turkey Tail.

    As such, the names of Yunzhi (as known in TCM), Coriolus Versicolor, Trametes versicolor (also known scientifically as Polystictus versicolor), Kawaratake (as known in Japan) and Turkey Tail (as known in North America) are the names commonly associated the same organic form of this organic mushroom product. While Polysaccharide Peptide (or PSP, as known in TCM) and Polysaccharide Krestin (or PSK, as known in Japan) are names commonly associated with the extracted, concentrated form of this polypore mushroom’s active ingredients.

Q2How is Yunzhi，PSP thought to treat mutation ailment？

    This polypore mushroom has shown immune enhancing, antimicrobial, antiviral and antitumor properties, which have been attributed to a protein-bound polysaccharide called Polysaccharide Peptide (PSP). PSP is not only capable of stimulating the immune system but also modulating mutative cell function and the tissue environment to facilitate the local destruction of mutative cells by activated immune effector cells.

    Since its discovery in 1971, over 350 scientific and clinical studies have been published demonstrating its potential benefits to a variety of diseases, especially mutation ailment. In China and in Japan, PSP/PSK is currently used as a mutation ailment treatment, in conjunction with surgery, chemotherapy and/or radiation.

Q3What has been proven about the benefits of Yunzhi，PSP？

· PSP is most effective when combined with a front-line serious illness treatment regimen (chemotherapy, radiation therapy or surgery) for patients with many types of mutation ailment. Randomized controlled clinical trials and meta-analysis showed that overall survival and disease-free survival are improved in patients treated with adjuvant immunotherapy plus PSP. PSP is also beneficial for maintaining general immune health with no reported adverse side effects.

· It minimizes the toxic and side effects caused by chemotherapy and radiotherapy. PSP can improve cancer survival by restoring and enhancing cellular immune functions in patients with depressed immunity due to radiation and/or chemotherapy or surgical stress after curative resection of the serious illness. As well, it has the ability to lower the cytotoxicity of certain clinical drugs via their interaction with cell cycle-dependent and apoptotic pathways.

· It alleviates common and undesirable symptoms suffered by patients, such as fatigue, poor appetite, adverse pain, anxiety, insomnia, nausea, vomiting, and spontaneous night sweat. Simply put, it improves the overall quality of life for its patients.

· It stabilizes the white blood cell count (white blood cells combat infections, regulates the intensive and duration of immunal response and mediate cell-to-cell communication) ; increases the activity of NK and LAK cells, reverses the CD4+ /CD8+ ratio; and raises the value of Karnofsky evaluation.

· Other non-immunological properties includes improvement of appetite and liver function, calming of the central nervous system and enhancement of pain threshold. With the benefit of the immuno-therapeutic as well as the non-immunological properties present, PSP can be taken in a daily regimen as a preventative measure as well as one’s general health maintenance.

Q4What are the adverese side effects associated with Yunzhi,PSP？

· PSP does not interact with other drugs nor affect hepatic drug-metabolizing enzyme activities indicating that drug efficacy is not affected by PSP when used with other medications. Although its anti-abnormal cell inhibitor effect is not as potent as that of chemotherapeutic drugs, PSP does not cause harm to the normal cells. In other words, PSP possesses the ability of distinguishing between normal and mutative cells.

· PSP is recorded as an anti-mutative fungal substance suited for treatment regimens used in mutative cell management by the American National Cancer Research Center but has not been evaluated by the Food and Drug Administration.

· WARNING: However, because of the active immuno-modulating benefits of PSP, organ-transplant patients should use extreme care. Consult your doctor before taken this product if you are currently on immune suppressant medication.

Q5What separates Wonder Herb's"Essence of Yunzhi"vs other brands？

· Our Yunzhi extracts are polysaccharide peptide (PSP) which has a much higher potent efficacy over PSK due to the bounding of peptide to polysaccharide during the process of extraction and production. Only when these two substances are bonded together, they can then be thoroughly absorbed by the human body and thus achieve the higher efficacy over other yunzhi production processes. The common misunderstanding is that the higher percentage of polysaccharide would lead to higher benefits. But, without the process of peptide bonded to polysaccharide, the polysaccharide is difficult to be absorbed within one’s body.

· Since the anti-mutative cell inhibiting ingredient of Yunzhi, protein bound polysaccharide, exists primarily in the mycelia, the strain Cov-1 used for our production of polysaccharide peptide (PSP) uses the deep layer cultivated mycelia as its raw material instead of using the crude fruit-body found in other brands. The mycelium is grown on an all-natural, chemical-free nutrient base and is produced through the deep layer cultivation method, yielding the most bioactively potent mycelium for raw material.

· Our PSP is not an ordinary Yunzhi water extract. The extraction technology of PSP is unique and its medicinal ingredients are isolated and purified from the raw Yunzhi. This is why our PSP is absolutely the essence of Yunzhi.

· The polysaccharide peptide content within each of our Essence of Yunzhi (PSP) 400mg capsule is over 70%, amongst the highest of all PSP brands in the market.

· To safeguard the highest standards in our products, all our “Essence of Yunzhi (PSP)” products are manufactured in Canada in accordance to the strictest Canadian certified Good Manufacturing Practice (GMP) standards in its factories.

· Upholding our commitment in maintaining the highest quality in our product, from the use of raw materials, to the stringent manufacturing standards in the Canadian certified GMP factories in our final product. It ensures our products are free of heavy metal, residual solvents or microbial toxins found in other brands.